SrasV1, 2020, Analysis, bibRecord, 000872

Cardiac and arrhythmic complications in patients with COVID-19.

Identifieur interne : 000872 ( 2020/Analysis ); précédent : 000871; suivant : 000873

Cardiac and arrhythmic complications in patients with COVID-19.

Auteurs : Adriano Nunes Kochi [Italie] ; Ana Paula Tagliari [Suisse] ; Giovanni Battista Forleo [Italie] ; Gaetano Michele Fassini [Italie] ; Claudio Tondo [Italie]

Source :

Journal of cardiovascular electrophysiology [ 1540-8167 ] ; 2020.

RBID : pubmed:32270559

Abstract

In December 2019, the world started to face a new pandemic situation, the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). Although coronavirus disease (COVID-19) clinical manifestations are mainly respiratory, major cardiac complications are being reported. Cardiac manifestations etiology seems to be multifactorial, comprising direct viral myocardial damage, hypoxia, hypotension, enhanced inflammatory status, ACE2-receptors downregulation, drug toxicity, endogenous catecholamine adrenergic status, among others. Studies evaluating patients with COVID-19 presenting cardiac injury markers show that it is associated with poorer outcomes, and arrhythmic events are not uncommon. Besides, drugs currently used to treat the COVID-19 are known to prolong the QT interval and can have a proarrhythmic propensity. This review focus on COVID-19 cardiac and arrhythmic manifestations and, in parallel, makes an appraisal of other virus epidemics as SARS-CoV, Middle East respiratory syndrome coronavirus, and H1N1 influenza.

DOI: 10.1111/jce.14479
PubMed: 32270559

Affiliations:

Links to Exploration step

pubmed:32270559

Le document en format XML

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<front><div type="abstract" xml:lang="en">In December 2019, the world started to face a new pandemic situation, the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). Although coronavirus disease (COVID-19) clinical manifestations are mainly respiratory, major cardiac complications are being reported. Cardiac manifestations etiology seems to be multifactorial, comprising direct viral myocardial damage, hypoxia, hypotension, enhanced inflammatory status, ACE2-receptors downregulation, drug toxicity, endogenous catecholamine adrenergic status, among others. Studies evaluating patients with COVID-19 presenting cardiac injury markers show that it is associated with poorer outcomes, and arrhythmic events are not uncommon. Besides, drugs currently used to treat the COVID-19 are known to prolong the QT interval and can have a proarrhythmic propensity. This review focus on COVID-19 cardiac and arrhythmic manifestations and, in parallel, makes an appraisal of other virus epidemics as SARS-CoV, Middle East respiratory syndrome coronavirus, and H1N1 influenza.</div>
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Cardiac and arrhythmic complications in patients with COVID-19.

Cardiac and arrhythmic complications in patients with COVID-19.

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Abstract

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